Understanding Peyronie’s Disease: Symptoms, Causes & Treatment Options

Peyronie’s disease is a condition that affects the structure and shape of the penis, often leading to a noticeable curvature, pain, and difficulties with sexual function. While it can be distressing, both physically and emotionally, effective treatment options are available—and early intervention often leads to the best outcomes.

In this post, we’ll explore what Peyronie’s disease is, what causes it, how to recognize the signs, and what treatments are available to help restore comfort and confidence.

What Is Peyronie’s Disease?

Peyronie’s disease is an acquired condition that involves the development of fibrous scar tissue (plaque) under the skin of the penis. This scar tissue affects the elasticity and structure of the penile shaft, which can lead to curvature, pain, and erection problems.

It is important to note that a slight bend in the penis can be perfectly normal. However, if the curvature becomes more pronounced or begins to interfere with sexual function or cause discomfort, it may be a sign of Peyronie’s.

Common Symptoms of Peyronie’s Disease

The signs of Peyronie’s disease can vary, but most men will experience one or more of the following:

1. Penile Curvature

The most recognizable symptom is a curved erection. The bend may be upward, downward, or sideways, depending on where the scar tissue forms.

2. Pain During Erection

Pain can occur during erections, particularly in the early stages of the disease. This may improve over time, but it can still cause significant discomfort.

3. Lumps or Hard Areas

You may feel hard plaques or lumps under the skin of the penis. These are typically the areas of scar tissue causing the bend.

4. Shortening or Narrowing

Scar tissue can reduce the flexibility of the penis, causing shortening or a narrowing effect sometimes referred to as an “hourglass” shape.

5. Erectile Dysfunction

The condition can interfere with blood flow, making it harder to achieve or maintain an erection. In severe cases, intercourse may become difficult or impossible.

Emotional Impact and Relationship Strain

Peyronie’s disease doesn’t just affect the body—it can also impact mental and emotional well-being. Men often experience feelings of:

Embarrassment
Anxiety
Frustration
Depression
Avoidance of intimacy

Studies show that nearly half of men with Peyronie’s disease report symptoms of depression. Relationship stress is also common, which is why open communication and early medical support are essential.

What Causes Peyronie’s Disease?

The exact cause is still under research, but Peyronie’s is believed to result from repeated minor trauma to the penis, such as bending or pressure during sexual activity. In men with a genetic predisposition or certain health conditions, this trauma can trigger an abnormal healing response, forming scar tissue.

Other Possible Contributing Factors Include:

Genetic factors
Vitamin E deficiency
Autoimmune conditions
Certain medications (such as beta blockers)
Elevated serotonin levels

In some cases, the condition may appear without a clear cause.

Diagnosis and Progression

A diagnosis is typically made through physical examination and medical history. A doctor may also assess the curvature by inducing an erection in a clinical setting to get an accurate evaluation of the plaque and deformity.

Peyronie’s can progress over time. Without treatment:

Around 48–76% of cases may worsen
Only 12% show spontaneous improvement
The rest may remain stable

Because of this, early diagnosis and treatment are crucial to avoid further complications and preserve sexual function.

Treatment Options for Peyronie’s Disease

There are several treatment strategies available for Peyronie’s disease. The right approach depends on how long you’ve had symptoms, the degree of curvature, and whether or not you’re experiencing pain or erectile dysfunction.

Here are four effective, non-surgical treatment options:

1. Shockwave Therapy

Shockwave therapy is a non-invasive treatment that uses acoustic waves to target the scar tissue. It can help reduce pain, stimulate blood flow, and may improve mild to moderate curvature. This therapy is often used in the early stages of Peyronie’s disease.

2. Trimix Injections

Trimix is a prescription medication that is injected directly into the penis to assist with erections. It can be useful in cases where Peyronie’s disease is accompanied by erectile dysfunction. While it doesn’t correct the curve, it can help men maintain firmer erections, making intercourse possible and less painful.

3. PRP Therapy (Platelet-Rich Plasma)

PRP therapy involves injecting concentrated platelets from your own blood into the affected area to support tissue healing. It is believed to help soften the plaque and improve penile blood flow. While still under ongoing research, PRP shows potential as a regenerative treatment for Peyronie’s-related tissue damage.

4. Sex Therapy

Because Peyronie’s disease often impacts self-esteem, intimacy, and relationships, sex therapy can be a critical part of treatment. A therapist can help you and your partner navigate the emotional and psychological effects of the condition while also exploring alternative ways to maintain sexual satisfaction and confidence.

Don’t Ignore the Signs—Early Action Matters

If you’ve noticed a curve in your penis, discomfort, or changes in erection quality, it’s important to seek help. Many men delay treatment due to embarrassment, but Peyronie’s disease is a medical condition that deserves attention and care.

The earlier you act, the more treatment options you’ll have. Addressing the condition in its early stages can help prevent progression, reduce the need for surgery, and improve both physical and emotional outcomes.

Expert Peyronie’s Treatment in Calgary

At Precision Clinic in Calgary, we provide professional evaluation and comprehensive treatment options for Peyronie’s disease. Our experienced team offers evidence-based therapies tailored to your specific condition and goals—whether you’re just starting to notice changes or are already struggling with symptoms.

You’ll receive compassionate, discreet care in a supportive environment.

Book a consultation today to explore your options and start your path to recovery.